HIIT scientists make a breakthrough in genome-wide epistasis analysis
Miikka2020-05-27T20:32:21+03:00Epistatic interactions between polymorphisms in DNA are recognized as important drivers of evolution in numerous organisms. Study of epistasis in bacteria has been hampered by the lack of densely sampled population genomic data, suitable statistical models and inference algorithms sufficiently powered for extremely high-dimensional parameter spaces. In an article published in PloS Genetics, a HIIT team introduced [...]